THE 2-MINUTE RULE FOR OXAZEPAM KRUIDVAT

Subacute toxicity scientific tests in dogs for 4 weeks at 480 mg/kg day by day confirmed no specific alterations; at 960 mg/kg, two outside of eight died with evidence of circulatory collapse. This extensive margin of safety is significant in comparison with chlordiazepoxide HCl, which confirmed nonspecific modifications in six puppies at 80 mg/kg.